Does flow reserve match contractility?

Does Flow Reserve Match Contractility ?

I have read with great interest the report by Barillà et al. (1). The data reported are intriguing because, to the best of my knowledge, this is the first report indicating that the restoration of regional contractility during low dose dobutamine administration may occur despite different perfusion patterns, depending on the presence or absence of collateral filling. Let me raise an issue not a...

Angiographic measurement of coronary blood flow reserve. Does it work?

T he study reported by Hess et all in this issue of Circulation presents a timely opportunity to discuss several issues that are directly relevant to use of angiographic methods for estimating myocardial perfusion. These issues are motivation for use of angiographic methods, limitations of the gold standard used, limitations of the angiographic method, limitations of the conceptual model used a...

Coronary flow reserve.

Fractional Flow Reserve

Traditionally, coronary artery disease was assessed using coronary angiographic guidance. Significant lesions were determined by the coronary angiographer. However, interobserver variability showed a significant limitation of interpretation of coronary angiography. Stent deployment and apposition were also evaluated based on angiographic appearance only. Risk factors for stent thrombosis and in...

Myocardial Blood Flow and Flow Reserve

Background. Aging is associated with changes of the systolic blood pressure that may increase cardiac work and myocardial blood flow at rest and reduce the myocardial flow reserve. This might be misinterpreted as age-related impairment of the coronary vasodilator capacity. Methods and Results. Myocardial blood flow was quantified at rest and after administration of intravenous dipyridamole in 4...